Tanespimycin - API

Product Name Tanespimycin - API
Product Code DA-T367-a
Chemical name Tanespimycin
Synonyms (4Z,6E,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate; Geldanamycin, 17-demethoxy-17-(2-propenylamino); 17-Demethoxy-17-(2-propenylamino)geldanamycin; 17-(Allylamino)-17-demethoxygeldanamycin; 17-(Allylamino)geldanamycin; 17-N-Allylamino-17-demethoxygeldanamycin;
Impurity NA
CAS Number 75747-14-7
Alternate CAS # NA
Molecular form C31H43N3O8
Appearance Dark Red to Very Dark Red Solid
Melting Point NA
Mol. Weight 585.7
Storage 2-8°C Refrigerator
Solubility NA
Stability NA
Category enzyme inhibitors,pharmaceutical standards,intermediates,enzyme activators
Boiling Point NA
Applications Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects. 17-AAG inhibits the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2.
Dangerous Goods Info NA
References NA
Extra Notes NA
Documents (MSDS) No Data Available
Keywords NA
Product Packings