Product

N-(2-Aminoethyl) Cyclopamine

Product Name N-(2-Aminoethyl) Cyclopamine
Product Code N00008890
Chemical name N-(2-Aminoethyl) Cyclopamine
Synonyms (2’R,3S,3’R,3’aS,6’S,6aS,6bS,7’aR,11aS,11bR)-4’-(2-aminoethyl)-1,2,3,3’a,4,4’,5’,6,6’,6a,6b,7,7’,7’a,8,11,11a,11b-octadecahydro-3’,6’,10,11b-tetramethyl-Spiro[9H-benzo[a]fluorene-9,2’(3’H)-furo[3,2-b]pyridin]-3-ol
Impurity
CAS Number 334616-31-8
Alternate CAS #
Molecular form C₂₉H₄₆N₂O₂
Appearance Off-White to Pale Beige Solid
Melting Point >140°C (dec.)
Mol. Weight 454.69
Storage -20°C Freezer
Solubility Chloroform (Slightly), Methanol (Slightly)
Stability
Category Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
Boiling Point
Applications A deriviative of Cyclopamine, which demonstrates teratogenic properties and has been shown to reverse effects ofoncogenic mutations in Smoothened and Patched.1
Dangerous Goods Info
References Taipale, J., et al.: Nature, 406, 1005 (2000), Perron, M., et al.: Development, 130, 1565 (2003)
Extra Notes
Documents (MSDS) No Data Available
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Product Packings
2.5mg
10mg
25mg