Product

AMG 837

Product Name AMG 837
Product Code A00009398
Chemical name AMG 837
Synonyms (βS)-β-1-Propynyl-4-[[4’-(trifluoromethyl)[1,1’-biphenyl]-3-yl]methoxy]-benzenepropanoic Acid; (βS)-β-1-Propyn-1-yl-4-[[4’-(trifluoromethyl)[1,1’-biphenyl]-3-yl]methoxy]benzenepropanoic Acid;
Impurity
CAS Number 865231-46-5
Alternate CAS #
Molecular form C₂₆H₂₁F₃O₃
Appearance
Melting Point
Mol. Weight 438.44
Storage
Solubility
Stability
Category
Boiling Point
Applications AMG 837 is a potent GPR40 agonist. GPR40 is a polyunsaturated fatty acid receptor that is involved with many systemic effects, which are beneficial for metabolic and inflammatory diseases. GPR40 has also been implicated as a target for treating obesity.
Dangerous Goods Info
References Dragano, N. R. V., et al.: J Neuroinflammation. 14, 91 (2017); Houze, J. B., et al.: Bioorg Med Chem Lett. 22, 1267 (2012)
Extra Notes
Documents (MSDS) No Data Available
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Product Packings
1mg
5mg
10mg
50mg