Product

17-(Allylamino-d5) Geldanamycin

Product Name 17-(Allylamino-d5) Geldanamycin
Product Code DA-G065-b
Chemical name 17-(Allylamino-d5) Geldanamycin
Synonyms 17-Demethoxy-17-(2-propenylamino-d5)geldanamycin; 17-(Allylamino-d5)-17-demethoxygeldanamycin; 17-(Allylamino-d5)-17-desmethylgeldanamycin; 17-Demethoxy-17-(allylamino-d5)geldanamycin; 17AAG-d5; CP 127374-d5; KOS 953-d5; NSC 330507-d5; Tanespimycin-d5; (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-((allyl-d5)amino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate;
Impurity NA
CAS Number NA
Alternate CAS # NA
Molecular form C31H38D5N3O8
Appearance Dark Purple Solid
Melting Point NA
Mol. Weight 590.72
Storage 2-8°C Refrigerator, Under Inert Atmosphere
Solubility NA
Stability NA
Category amines,heterocycles,enzyme inhibitors,pharmaceutical standards,intermediates,Fine Chemicals,stable isotopes
Boiling Point NA
Applications Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects. 17-AAG inhibits the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2.
Dangerous Goods Info NA
References NA
Extra Notes NA
Documents (MSDS) No Data Available
Keywords NA
Product Packings