17-(Allylamino-d5) Geldanamycin
| Product Name |
17-(Allylamino-d5) Geldanamycin
|
| Product Code |
DA-G065-b
|
| Chemical name |
17-(Allylamino-d5) Geldanamycin
|
| Synonyms |
17-Demethoxy-17-(2-propenylamino-d5)geldanamycin; 17-(Allylamino-d5)-17-demethoxygeldanamycin; 17-(Allylamino-d5)-17-desmethylgeldanamycin; 17-Demethoxy-17-(allylamino-d5)geldanamycin; 17AAG-d5; CP 127374-d5; KOS 953-d5; NSC 330507-d5; Tanespimycin-d5; (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-((allyl-d5)amino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate;
|
| Impurity |
NA
|
| CAS Number |
NA
|
| Alternate CAS # |
NA
|
| Molecular form |
C31H38D5N3O8
|
| Appearance |
Dark Purple Solid
|
| Melting Point |
NA
|
| Mol. Weight |
590.72
|
| Storage |
2-8°C Refrigerator, Under Inert Atmosphere
|
| Solubility |
NA
|
| Stability |
NA
|
| Category |
amines,heterocycles,enzyme inhibitors,pharmaceutical standards,intermediates,Fine Chemicals,stable isotopes
|
| Boiling Point |
NA
|
| Applications |
Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects. 17-AAG inhibits the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2.
|
| Dangerous Goods Info |
NA
|
| References |
NA
|
| Extra Notes |
NA
|
| Documents (MSDS) |
No Data Available
|
| Keywords |
NA |
