1-(2-Amino-5-hydroxyphenyl)propan-1-one
| Product Name |
1-(2-Amino-5-hydroxyphenyl)propan-1-one
|
| Product Code |
DA-I045-p
|
| Chemical name |
1-(2-Amino-5-hydroxyphenyl)propan-1-one
|
| Synonyms |
2'-Amino-5'-hydroxypropiophenone; Irinotecan - In house impurity
|
| Impurity |
NA
|
| CAS Number |
35364-15-9
|
| Alternate CAS # |
NA
|
| Molecular form |
C9H11NO2
|
| Appearance |
Yellow to Beige Solid
|
| Melting Point |
NA
|
| Mol. Weight |
165.19
|
| Storage |
2-8°C Refrigerator, Under inert atmosphere
|
| Solubility |
NA
|
| Stability |
NA
|
| Category |
impurities,metabolites,intermediates,pharmaceutical standards,fine chemicals
|
| Boiling Point |
NA
|
| Applications |
1-(2-Amino-5-hydroxyphenyl)propan-1-one is a useful synthetic intermediate. It is used in the asymmetrical synthesis of (S)-4-ethyl-6,7,8,10- tetrahydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione, a key intermediate for synthesis of irinotecan and other camptothecin analogs. It is also used in the synthesis of E-ring-modified (RS)-camptothecin analogs as antitumor agents.
|
| Dangerous Goods Info |
NA
|
| References |
NA
|
| Extra Notes |
NA
|
| Documents (MSDS) |
No Data Available
|
| Keywords |
NA |
