Lapaquistat-d9 Acetate

Product Name Lapaquistat-d9 Acetate
Product Code DA-L116-b
Chemical name Lapaquistat-d9 Acetate
Synonyms 1-[2-[(3R,5S)-1-[3-(Acetyloxy)-2,2-dimethylpropyl]-7-chloro-5-(2,3-dimethoxyphenyl)-1,2,3,5-tetrahydro-2-oxo-4,1-benzoxazepin-3-yl]acetyl]-4-piperidineacetic Acid-d9; (3R-trans)-1-[[1-[3-(acetyloxy)-2,2-dimethylpropyl]-7-chloro-5-(2,3-dimethoxyphenyl)-1,2,3,5-tetrahydro-2-oxo-4,1-benzoxazepin-3-yl]acetyl]-4-piperidineacetic Acid-d9; TAK 475-d9;
Impurity NA
CAS Number 1292841-28-1
Alternate CAS # NA
Molecular form C33H32D9ClN2O9
Appearance NA
Melting Point NA
Mol. Weight 654.20
Storage 2-8°C Refrigerator
Solubility NA
Stability NA
Category amines,chiral standards,heterocycles,enzyme inhibitors,stable isotopes,pharmaceutical standards,intermediates,fine chemicals
Boiling Point NA
Applications A novel labelled squalene synthase inhibitor. Lapaquistat acetate decreased plasma cholesterol and triglyceride levels, by lowering lipoproteins containing apoB100. Treatment with Lapaquistat acetate increased collagen concentration and transformed coronary plaques into fibromuscular plaques. Lapaquistat acetate also suppressed the expression of matrix metalloproteinase-1 and plasminogen activator inhibitor-1 in the plaque and increased peripheral coenzyme Q10 levels. Antiarteriosclerotics.
Dangerous Goods Info NA
References NA
Extra Notes NA
Documents (MSDS) No Data Available
Keywords NA
Product Packings