| Product Name | Teriflunomide-3-isomer |
| Product Code | DA-T037-o |
| Chemical name | Teriflunomide-3-isomer |
| Synonyms | 2-Cyano-3-hydroxy-N-[3-(trifluoromethyl)phenyl]-2-butenamide; 2-Butenamide, 2-cyano-3-hydroxy-N-[3-(trifluoromethyl)phenyl]-; |
| Impurity | NA |
| CAS Number | 62004-05-1 |
| Alternate CAS # | NA |
| Molecular form | C12H9F3N2O2 |
| Appearance | NA |
| Melting Point | NA |
| Mol. Weight | 270.21 |
| Storage | 2-8°C Refrigerator |
| Solubility | NA |
| Stability | NA |
| Category | intermediates,impurities,pharmaceutical standards,Fine Chemicals,metabolites,tyrosine kinase inhibitors |
| Boiling Point | NA |
| Applications | 2-Cyano-3-hydroxy-N-[3-(trifluoromethyl)phenyl]-2-butenamide is a derivative of Leflunomide which is an immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutically as a antirheumatic (Merck Index). This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research. |
| Dangerous Goods Info | NA |
| References | NA |
| Extra Notes | NA |
| Documents (MSDS) | No Data Available |
| Keywords | NA |
