1-(3-Chlorophenyl)piperazine
| Product Name |
1-(3-Chlorophenyl)piperazine
|
| Product Code |
DA-T190-l
|
| Chemical name |
1-(3-Chlorophenyl)piperazine
|
| Synonyms |
Trazodone Hydrochloride Impurity L (EP/BP); 1-(m-Chlorophenyl)piperazine; 4-(3-Chlorophenyl)piperazine; N-(3-Chlorophenyl)piperazine; N-(m-Chlorophenyl)piperazine; meta-Chlorophenylpiperazine; mCPP;
|
| Impurity |
NA
|
| CAS Number |
6640-24-0
|
| Alternate CAS # |
NA
|
| Molecular form |
C10H13ClN2
|
| Appearance |
Colourless Oil
|
| Melting Point |
NA
|
| Mol. Weight |
196.68
|
| Storage |
2-8°C Refrigerator, Under inert atmosphere
|
| Solubility |
NA
|
| Stability |
NA
|
| Category |
intermediates
|
| Boiling Point |
NA
|
| Applications |
It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone (1,2,3). The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone.
|
| Dangerous Goods Info |
NA
|
| References |
NA
|
| Extra Notes |
NA
|
| Documents (MSDS) |
No Data Available
|
| Keywords |
NA |
