| Product Name | Tanespimycin - API |
| Product Code | DA-T367-a |
| Chemical name | Tanespimycin |
| Synonyms | (4Z,6E,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate; Geldanamycin, 17-demethoxy-17-(2-propenylamino); 17-Demethoxy-17-(2-propenylamino)geldanamycin; 17-(Allylamino)-17-demethoxygeldanamycin; 17-(Allylamino)geldanamycin; 17-N-Allylamino-17-demethoxygeldanamycin; |
| Impurity | NA |
| CAS Number | 75747-14-7 |
| Alternate CAS # | NA |
| Molecular form | C31H43N3O8 |
| Appearance | Dark Red to Very Dark Red Solid |
| Melting Point | NA |
| Mol. Weight | 585.7 |
| Storage | 2-8°C Refrigerator |
| Solubility | NA |
| Stability | NA |
| Category | enzyme inhibitors,pharmaceutical standards,intermediates,enzyme activators |
| Boiling Point | NA |
| Applications | Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects. 17-AAG inhibits the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2. |
| Dangerous Goods Info | NA |
| References | NA |
| Extra Notes | NA |
| Documents (MSDS) | No Data Available |
| Keywords | NA |
